Childhood bilateral limbal stem cell deficiency: long-term management and outcome
نویسندگان
چکیده
منابع مشابه
Long-term Outcome of Limbal Stem Cell Transplantation for the Management of Total Limbal Stem Cell Deficiency due to a Chemical Burn
Purpose: To evaluate the long-term outcome of limbal stem cell transplantation (LSCT) for the management of total limbal stem cell deficiency (LSCD) due to chemical burn in Labbafinejad Medical Center (LMC). Methods: Records of patients with a history of severe (i.e. grade III and IV) chemical burns, who were referred to LMC and underwent LSCT, were reviewed and data including demographic chara...
متن کاملTherapeutic Options for Patients with Bilateral Limbal Stem Cell Deficiency
Purpose: Live-related conjunctival-limbal allografting (Lr-CLAL), allogeneic cultivated limbal epithelial transplantation (allo-CLET). autologous cultivated oral mucosal epithelial transplantation (COMET) and Boston Type 1 Keratoprosthesis (Boston Kpro) are the four most widely performed procedures for patients with bilateral limbal stem cell deficiency (LSCD) with wet ocular surfaces. This stu...
متن کاملLimbal stem-cell therapy and long-term corneal regeneration.
BACKGROUND Corneal renewal and repair are mediated by stem cells of the limbus, the narrow zone between the cornea and the bulbar conjunctiva. Ocular burns may destroy the limbus, causing limbal stem-cell deficiency. We investigated the long-term clinical results of cell therapy in patients with burn-related corneal destruction associated with limbal stem-cell deficiency, a highly disabling ocu...
متن کاملLong-term outcome of keratolimbal allograft with or without penetrating keratoplasty for total limbal stem cell deficiency.
PURPOSE To evaluate the long-term outcome of ocular surface reconstruction, including keratolimbal allograft (KLAL) and amniotic membrane transplantation (AMT) with or without penetrating keratoplasty (PKP), in patients with nonambulatory vision secondary to total limbal stem cell deficiency (LSCD). DESIGN Retrospective, non-comparative interventional case series. PARTICIPANTS Thirty-nine e...
متن کاملLimbal Stem Cell Deficiency and Treatment with Stem Cell Transplantation
The cornea is the outermost tissue of the eye and it must be transparent for the maintenance of good visual function. The superficial epithelium of the cornea, which is renewed continuously by corneal stem cells, plays a critical role in the permanence of this transparency. These stem cells are localized at the cornea-conjunctival transition zone, referred to as the limbus. When this zone is af...
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ژورنال
عنوان ژورنال: Case Reports
سال: 2013
ISSN: 1757-790X
DOI: 10.1136/bcr-2013-009508